In-Vivo Calcium Imaging
Mightex OASIS Implant
Freely-Behaving Imaging and Optogenetics
The OASIS Implant is a ground-breaking platform for simultaneous cellular-resolution optogenetics and calcium imaging in freely-behaving animals to probe complex neuronal networks.To offer neuroscientists the ability to stimulate and visualize individual neurons in freely-behaving animals, Mightex’s engineers went back to the drawing board and pioneered a new path in the in vivo calcium imaging field. Instead of miniaturizing and placing the microscope on the animal – thereby limiting the microscope’s features and the animal’s behaviour – we kept the microscope off the animal’s head by using an imaging fiber.
By keeping the microscope away from the animal’s head, the OASIS Implant accomplishes 2 main goals:
1. Maximize Microscope Performance; Integrated Patterned Stimulation, Unlimited Illumination Sources, Scientific-Grade Cameras.
2. Optimize Behaviour; Compact and up to 3x lighter headmount. No electronics on the head of the animal.
Mightex OASIS Macro
Mesoscopic Optical Imaging and Optogenetics
The OASIS Macro is a mesoscope for all-optical targeted optogenetics, calcium imaging, and intrinsic imaging. The OASIS Macro enables researchers to simultaneously image the entire mouse cortex and perform targeted optogenetics (with Mightex’s market-leading Polygon DMD illuminator).Mightex’s OASIS Macro is designed as a reconfigurable mesoscope for in vivo imaging and optogenetics. The final system can be tailored to performance requirements for unique applications. This can include major features such as adding a second and third illumination source, or a dual-camera imaging system, as well as fine details including compatibility features for certain cameras and objectives.
Mightex OASIS Micro
Local Population Imaging and Optogenetics
The OASIS Micro is a ground-breaking microscope platform for all-optical cellular-resolution optogenetics and imaging in small cortical or deep-brain areas of a head-fixed animal. Simultaneously image small cortical or deep brain regions and perform neuron-specific targeted optogenetics with the addition of Mightex’s Polygon pattern illuminator.Mightex’s OASIS Micro is designed as a reconfigurable optical microscope system for in vivo imaging and optogenetics. The final system can be tailored to performance requirements for unique applications. This can include major features such as adding a second and third illumination source, or a dual-camera imaging system, as well as fine details including compatibility features for certain cameras and objectives.
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