Optogenetics Stimulation
Mightex Polygon
DMD Pattern Illuminator for Targeted Photostimulation
Mightex’s market-leading Polygon DMD pattern illuminator provides precise spatiotemporal control of light with subcellular resolution, making it the perfect illumination tool for life science research.The Polygon uses digital mirror device (DMD) technology to illuminate multiple regions simultaneously. A DMD is composed of hundreds of thousands of micro-mirrors that can be individually turned on to reflect light onto the sample. Thus, you can control each mirror to control the area(s) of illumination and create any number of different sized patterns. The Polygon DMD pattern illuminator can be mounted into the infinity-path of any microscope.
Mightex Polygon 1000-G
Lightguide-input, ‘Standard’ Pattern Illuminator
The Polygon1000-G is a flexible solution for patterned illumination, as this patterned illuminator can be used with any lightsource (350-1000nm) that accepts a 3mm core lightguide. Thus, the Polygon1000-G provides future flexibility for different wavelengths and lightsources, depending on your application.Wavelengths: 350-1000nm*
Lightsource: lightguide-coupled
Add-on front tube available for large field of view
Mightex Polygon 1000-DL
Fiber-input, with Higher Optical Output for a Large FoV
The Polygon1000-DL is a flexible solution for a large field of view or high-power patterned illumination applications, as this patterned illuminator can be used with any fiber-coupled lightsource (400-1000nm), such as high-power lasers. This Polygon1000 model has been designed for high-power applications, such as in vivo optogenetics.Wavelengths: 400-1000nm
Lightsource: fiber-coupled
Mightex Polygon UHC
Ultra High Contrast DMD Pattern Illuminator
Mightex’s market-leading Polygon DMD pattern illuminators provide precise spatiotemporal control of light with subcellular resolution, making them the perfect illumination tool for life science research. The Polygon UHC incorporates the latest in digital micromirror technology to achieve the greatest available contrast ratio of 10,000,000:1, unlocking countless research opportunities for the bioscience community.The latest digital micromirror technology in the Polygon UHC achieves market-leading contrast ratio. That is, the greatest ratio of the light intensity of an all-on image to an all-off image. The higher the contrast, the better the background light can be suppressed.
Mightex Microscopy LEDs
For many bioscience applications such as optogenetics, precisely-timed and high-intensity light pulses are required to activate channelrhodopsins (ChR2, ChR1 etc.) and halorhodopsins (NpHR), in order to excite and/or inhibit neurons using a microscopy light source. Other applications, such as Calcium imaging or voltage imaging, call for light sources which offer not only powerful and stable illumination, but also fast response time and long lifetime. Mightex has developed a wide range of market-leading BioLED sources for such applications.
Mightex Fiber-Coupled LEDs
Mightex fiber-coupled light sources are modularized fully-customizable turn-key solutions for optogenetics, fluorescence excitation, and other biophotonics applications. For example, precisely-timed and high-intensity light pulses are required in optogenetics experiments to activate channelrhodopsins (ChR2, ChR1 etc.) and halorhodopsins (NpHR) in order to excite and inhibit neurons. Mightex has developed a comprehensive portfolio of FCS-series single-wavelength and WFC-series multi-wavelength fiber-coupled LEDs, in order to meet a wide range of bioscience research needs.
Mightex Lightguide-Coupled LEDs
Mightex BLS-series BioLED light sources are modularized fully-customizable turn-key solutions for optogenetics, fluorescence excitation, and other biophotonics applications. Precisely-timed and high-intensity light pulses are required in optogenetics experiments to activate channelrhodopsins (ChR2, ChR1 etc.) and halorhodopsins (NpHR) in order to excite and inhibit neurons. To meet these requirements, Mightex has developed a proprietary “IntelliPulsing” technology to allow BLS-series sources to output significantly higher power in pulse mode than what the LEDs are rated for in CW mode.
Mightex Spotlight LEDs
Mightex BLS-series precision LED spotlight employ the latest high-power LED technologies and a proprietary coupling optics to achieve the best beam uniformity. In conjunction with BioLED light source control modules, these LED sources can be used for a wide range of applications including optogenetics and other bio-photonics applications.
Mightex Manual/Analog LED Controllers
Mightex BLS-1000-2, BLS-3000-2, BLS-13000-1, and BLS-18000-1 LED controllers are designed for driving Mightex LED sources. The controllers have two operation modes:
Manual Mode: the output current can be controlled by manually turning the knobs; or
Trigger Mode: the output current can be controlled via an external analog input signal between 0 ~ 5V.
The control mode is selected with a slide switch on the front panel, and the factory default is “Manual” mode. BLS-1000-2 and BLS-3000-2 provide Maximum Current Selection DIP switches on the rear panel, which allow the user to set the maximum output current of the channel to 500/750/1,000mA for BLS-1000-2, and 1,000/2,000/3,000mA for BLS-3000-2, respectively. The factory default is set to 500mA for BLS-1000-2 and 1,000mA for BLS-3000-2, respectively. BLS-13000-1 and BLS-18000-1 has only one maximum current setting of 13,000mA and 18,000mA, respectively.
When the controller is set to “Trigger” mode, the output current is fully controlled by the input analog signal (0-5V).
Mightex Multi-Wavelength Collimated LED Sources
Multiple LED sources can be efficiently combined into a single output beam, and offer major advantages such as long life-time, easily tunable spectrum, high power stability, and ultra-fast switching (on the microseconds level) without using moving mechanical components. Multi-Wavelength Collimated LED Sources find many applications in microscopy, spectroscopy, chemistry, and other physical science application, where light in different wavelengths can be combined into a single collimated output beam that is often further coupled into an optical systems. The highly collimated multi-wavelength output beam is suitable for working with lenses, filters, dichroic, mirrors, and many other optical components, while simultaneously allowing the user to tailor the spectrum to best suit the specific application requirements.
When the controller is set to “Trigger” mode, the output current is fully controlled by the input analog signal (0-5V).
Scientifica HoloStim-3D
Acquire high-quality images and maximise your photon collection when performing multiphoton fluorescence imaging.
The HoloStim-3D seamlessly integrates with the HyperScope and VistaScope award-winning multiphoton imaging systems, to create an industry-leading spatial light modulator (SLM) system for all-optical interrogation of neural networks with previously unachievable performance.
CoolLED pE-300ultra
LED illumination for in-vitro optogenetics and high-speed fluorescence microscopy.
Intense, broad-spectrum LED illumination for imaging most common fluorescent stains. Users have access to both microsecond switching via multiple TTL inputs and the ability to mount inline excitation filters. This, when paired with today’s high performance multi band filter sets, facilitates imaging traditionally done via a white light source and a filter wheel, with all the benefits of LED.CoolLED pE-800
With eight individually controllable LEDs and fast TTL switching, the pE-800 takes centre stage as the widefield illumination method of choice.
Versatile and intuitive the pE-800 with liquid light guide delivery makes next generation LED illumination accessible to all.Want to know more?
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